Selective recognition of pyrophosphate in water using a backbone modified cyclic peptide receptor.
نویسندگان
چکیده
A cyclic peptide based receptor, bearing two dipicolylamino arms complexed to zinc(II) ions, binds pyrophosphate ions with high affinity and selectivity in aqueous solution as determined using an indicator displacement assay.
منابع مشابه
Selective sensing of pyrophosphate in physiological media using zinc(II)dipicolylamino-functionalised peptides.
A series of linear peptide based anion receptors, in which the distance between the bis[zinc(II)dipicolylamine] binding sites and the peptide backbone was varied systematically, was prepared and their anion binding ability was investigated using indicator displacement assays. Shortening the distance between the binding site and the peptide backbone was found to enhance both the receptor affinit...
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عنوان ژورنال:
- Chemical communications
دوره 28 شماره
صفحات -
تاریخ انتشار 2006